Archives of Papers
Publications
2004
Harden RN, Rudin NJ, Bruehl S, et al. Increased systemic catecholamines in complex regional pain syndrome and relationship to psychological factors: a pilot study. Anesth Analg. 2004;99(5):1478-1485; table of contents.
2005
Kuiken TA, Schechtman L, Harden RN. Phantom limb pain treatment with mirtazapine: A case series. Pain Practice. 2005 5(4):356-360.
Harden RN, Houle TT, Remble TA, Lin W, Wang K, Saltz S. Topiramate for phantom limb pain: a time-series analysis. Pain Med. Sep-Oct 2005;6(5):375-378.
Harden RN, Weinland SR, Remble TA, et al. Medication Quantification Scale Version III: update in medication classes and revised detriment weights by survey of American Pain Society Physicians. J Pain. Jun 2005;6(6):364-371.
Harden RN, Houle TT, Green S, et al. Biofeedback in the treatment of phantom limb pain: a time-series analysis. Appl Psychophysiol Biofeedback. Mar 2005;30(1):83-93.
2006
Baliki MN, Chialvo DR, Geha PY, Levy RM, Harden RN, Parrish TB, Apkarian AV. Chronic Pain and the Emotional Brain: Specific Brain Activity Associated with Spontaneous Fluctuations of Intensity of Chronic Back Pain. Journal of Neuroscience 2006; Nov. 26(47) 12165-73.
2007
Geha PY, Baliki MN, Chialvo DR, Harden RN, Paice JA, Apkarian AV. Brain Activity for Spontaneous Pain of Postherpetic Neuralgia and its Modulation by Lidocaine Patch Therapy. Pain 2007; 128 88-900.
Harden RN, Bruehl S, Stanton-Hicks M, Wilson PR. Proposed New Diagnostic Criteria for Complex Regional Pain Syndrome. Pain Medicine 2007; 8(4) 326-331.
Harden RN, Remble TA, Houe TT, Long JF, Markov MS, Gallizzi MA. Prospective, Randomized, Single-Blind, Sham Treatment-Controlled Study of the Safety and Efficacy of an Electromagnetic Field Device for the Treatment of Chronic Low Back Pain: A Pilot Study. Pain Practice 2007; 7(3) 248-255.
Harden RN, Revivo G, Song S, Nampiaparampil D, Golden G, Kirincic M, Houle TT. A Critical Analysis of the Tender Points in Fibromyalgia. Pain Medicine 2007; 8(2) 147-156.
Kuiken TA, Marasco PD, Lock BA, Harden RN, Dewald, JPA. Redirection of Cutaneous Sensation from the Hand to the Chest Skin of Human Amputees with Targeted Reinnervation. PNAS Proceedings of the National Academy of Sciences of the United States of America 2007; Dec. 104(50) 20061-66.
Mogilevsky M, Janig W, Baron R, Harden RN. Complex Regional Pain Syndrome: A Multifaceted Disorder Requiring Multidimensional Care: Case Study. Journal of Pain 2007; 8(9) 687-681.
2008
Baliki M, Geha P, Jabakhanji R, Harden RN, Schnitzer T, Apkarian AV. A Preliminary fMRI Study of Analgesic Treatment in Chronic Back Pain and Knee Osteoarthritis. Molecular Pain 2008; Oct. 4-47.
Gallizzi M, Gagnon C, Harden RN, Stanos S, Kahn A. Medication Quantification Scale Version III: Internal Validation of Detriment Weights using a Chronic Pain Population. Pain Practice 2008; 8(1) 1-4.
Geha P, Baliki M, Harden RN, Bauer W, Parrish T, Apkarian A. The Brain in Chronic CRPS Pain: Abnormal Gray-White matter Interactions in Emotional and Autonomic Regions. Neuron 2008; 6(4) 570-581.
Harden RN, Gagnon CM, Gallizi M, Khan AS, Newman D. Residual Limbs of Amputees are Significantly Cooler than Contralateral Intact Limbs. Pain Practice 2008; 8(5) 342-347.
Tu FF, Fitzgerald CM, Kuiken T, Farrell T, Norman Harden R. Vaginal Pressure-Pain Thresholds: Initial Validation and Reliability Assessment in Healthy Women. Clinical Journal of Pain 2008; Jan. 24(1) 45-50.
2009
Harden RN, Cottrill J, Gagnon CM, Smitherman TA, Weinland SR, Tann B, Joseph P, Lee TS, Houle TT. Botulinum Toxin A in the Treatment of Chronic Tension-Type Headache with Cervical Myofascial Trigger Points: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. Headache 2009; 49(5) 732-743.
Nampiaparampil DE, Nampiaparampil JX, Harden RN. Pain and Prejudice. Pain Med 2009; 10(4) 716-21.
2010
Harden RN. Objectification of the Diagnostic Criteria for CRPS. Pain Medicine 2010; 11(8) 1212-1215.
Harden RN, Bruehl S, Perez RSGM, Birklein F, Marinus J, Maihofner C, et al. Validation of Proposed Diagnostic Criteria (the “Budapest Criteria”) for Complex Regional Pain Syndrome. Pain 2010; 150 268-274.
Harden RN, Bruehl S, Perez RSGM, Birklein F, Marinus J, Maihofner C, et al. Development of a Severity Score for CRPS. Pain 2010; 151 870-876.
Harden RN, Gagnon CM, Graciosa J, Gould EM. Negligible Analgesic Tolerance Seen with Extended Release Oxymorphone: A Post Hoc Analysis of Open-Label Longitudinal Data. Pain Medicine 2010; 11 1198-1208.
Harden RN, Gagnon CM, Khan A, Wallach G, Zereshki A. Hypoesthesia in the Distal Residual Limb of Amputees. Physical Medicine and Rehabilitation 2010; 2(7) 607-611.
Ramsden C, Gagnon C, Graciosa J, Faurot K, David R, Bralley A, Harden RN. Do Omega-6 and Trans Fatty Acids Play a Role in Complex Regional Pain Syndrome? A Pilot Study. Pain Medicine 2010; 11 1115-1125.
Swank S, Harden RN. Somatic Dysfunction in Amputees: A Pilot Study. Physical Medicine and Rehabilitation 2010; S66.
Swank S, Weber N, Fleming N, Harden RN. Sympathetic Autonomic Exacerbation of Phantom Limb Pain: A Pilot Study. Journal of the American Osteopathic Association 2010; 110(8) 448.
Zinke JL, Lam CS, Harden RN, Fogg L. Examining the Cross-Cultural Validity of the English Short-Form McGill Pain Questionnaire using the Matched Moderated Regression Methodology. The Clinical Journal of Pain 2010; 26 (2) 153-162.
Reviews, Chapters, Books
2006
Carr DB, Harden RN, eds. Pain after Landmine Injury: Origins, Impact, and Management: A Guide to Postamputation Care. Pain Medicine 2006; 7(suppl 2) S195-S222.
Harden RN, ed. Complex Regional Pain Syndrome: Treatment Guidelines. Milford, CT: RSDSA Press, 2006.
Harden RN. Diagnostic Considerations. Journal of Neuropathic Pain & Symptom Palliation 2006; 2(3) 41-45.
Harden RN. Interdisciplinary Management/Functional Restoration. Journal of Neuropathic Pain & Symptom Palliation 2006; 2(3) 45-51.
Harden RN. Neuropathic Pain. In von Roenn JH, Paice JA, Preodor ME, eds. Current Diagnosis and Treatment of Pain. Chicago: McGraw-Hill Companies, Inc., 2006: 122-135.
Harden RN. Pharmacotherapy. In Harden RN, ed. Complex Regional Pain Syndrome: Treatment Guidelines. Milford, CT: RSDSA Press, 2006: 25-36.
Harden RN, et al. Diagnostic and Treatment Issues in Post Amputation Pain after Landmine Injury. Pain Med 2006; 7(Suppl 2) S209-S212.
Harden RN, et al. Neurophysiology of Pain from Landmine Injury. Pain Medicine 2006; 7(Suppl 2) S204-S208.
Harden RN, Bruehl S. Diagnosis of Complex Regional Pain Syndrome: Signs, Symptoms, and New Empirically Derived Diagnostic Criteria. Clinical Journal of Pain 2006; 22(5) 415-419.
Harden RN, Bruehl S. Introduction and Diagnostic Considerations. In Harden RN, ed. Complex Regional Pain Syndrome: Treatment Guidelines. Milford, CT: RSDSA Press, 2006: 1-11.
Harden RN, Swan M, Costa B, Barthel J, King A. Interdisciplinary Management. In Harden RN, ed. Complex Regional Pain Syndrome: Treatment Guidelines. Milford, CT: RSDSA Press, 2006: 12-24.
Harden RN, Swan M, Costa B, Barthel J, King A. Treatment of Complex Regional Pain Syndrome: Functional Restoration. Clinical Journal of Pain 2006; 22(5) 420-424.
Geertzen J, Harden RN. Physical and Occupational Therapies in Complex Regional Pain Syndrome Type I. Journal of Neuropathic Pain & Symptom Palliation 2006; 2(3) 56-69.
Stanos SP, Tyburski MD, Harden RN. Management of Chronic Pain. In Braddom RL, Buschbacher RM, eds. Physical Medicine and Rehabilitation. 3rd ed. Philadelphia: W. B. Saunders Company, 2006.
2007
Harden RN. Clinical Corner Q&A: Is there any Research or Rationale for using Duloxitene (Cymbalta) for the Treatment of CRPS? RSDSA Newsletter. 2007; 20(1) RSDSA Press: Milford, CT: 9.
Harden RN. CRPS: Diagnostic Considerations. In CRPS: Current Diagnosis and Therapy. Lindgren KA, ed. Rehabilitation ORTON Invalid Foundation, 2007: Helsinki, Finland: 7-13.
Harden RN. CRPS: Interdisciplinary Management and Functional Restoration. In: CRPS: Current Diagnosis and Therapy. Lindgren KA, ed. Rehabilitation ORTON Invalid Foundation, 2007: Helsinki, Finland: 63-75.
Harden RN. Muscle Pain Syndromes. American Journal of Physical Medicine Rehabilitation 2007; 86(Suppl.) S47-S58.
2008
Harden RN. Chronic Pain and Opiates: A Call for Moderation. Archives of Physical Medicine and Rehabilitation 2008; Mar. 89(Suppl.) S72-S76.
2009
Harden, RN. Editorial regarding the “Relationship between Pain and Neuropathic Symptoms in Chronic Musculoskeltal Pain” by Dr. Giske et al. Pain Med 2009; 10(5) 780.
Harden RN. Interdisciplinary Management for Complex Regional Pain Syndrome. Current Therapy in Pain. Smith, HS ed. Saunders Elsevier 2009: Philadelphia, PA: 309-315.
2010
Harden RN. Complex Regional Pain Syndrome Workshop at Cardiff. Pain Medicine 2010; 11(11) 1146.
Harden RN. War is Hell. Pain Medicine 2010; 11(12) 1753.
Rauck R, Harden RN, Jimenez T, McClung C, Graff O. A randomized, placebo-controlled trial of gabapentin enacarbil in subjects with post-herpetic neuralgia. The Journal of Pain. 2010; 11 (S41).
Richeh W, Harden RN. Mechanical Hyperesthesia and Cold Perception Hypoesthesia in Distal Residual Limbs of Amputees. The Journal of Pain. 2010; 11 (S13).
Saracoglu M, Wallach G, Gagnon C, Harden RN. Diagnostic and Psychophysical Correlates of Chronic Pain in the Osteoarthritis Knee Model. The Journal of Pain 2010; 11 (S13).
Current Reviews in Musculoskeletal Medicine 2010. In press.
Tahaei A, Sarin R, Graciosa J, Oswald M, Harden RN. Comparison of Sympathetic Skin Response and Skin Conductance Response in Spinal Cord Injury Pain Subjects. The Journal of Pain. 2010; 11 (S4).
2011
Harden RN. Cytokine imbalance/activity as a unifying hypothesis for the pathogenesis and pathophysiology of Complex Regional Pain Syndrome? Pain 2011; 152(2):247-8.
Abstracts
2006
Tu FF, Fitzgerald CM, Kuiken T, Farrell T, Harden RN. Pressure-pain thresholds to diagnose pelvic floor myofascial pain syndrome. Poster presented at: The American Pain Society Annual Conference. San Antonio, TX; May 2006.
Gallizzi M, Graciosa J, Egyhazi R, Gagnon CM, Harden RN. Case Report: Nerve Recovery in a Patient with Benign Idiopathic Trigeminal Sensory Neuropathy Evaluated by Quantitative Sensory Testing. Midwest Pain Society, 2006; Chicago, IL.
Tu FF, Fitzgerald CM, Kuiken T, Fararell T, Harden RN. Pressure-pain thresholds to diagnose pelvic floor myofascial pain syndrome. Poster presented at: The Midwest Pain Society. Chicago, IL; September 2006.
Geha PY, Narang A, Baliki MN, Harden RN, Bauer W, Chialvo DR, Apkarian AV. Fractional anisotropy of white matter tract contrasted between complex regional pain syndrome and normal controls. Poster presented at: The Society for Neuroscience Annual Meeting. Atlanta, GA; October 2006.
Gagnon CM, Stanos S, Rader L, Gallizzi M, Harden RN. A preliminary examination of potential outcome predictors for an interdisciplinary pain management program. Poster presented at: The American Academy of Physical Medicine and Rehabilitation 67th Annual Assembly and Technical Exhibition. Honolulu, HI; November 2006.
Harden RN, Khan AS, Gagnon CM, Daschbach P, DiMaio A, Kuiken T. The assessment of quantitative sensory testing in post-amputation patients. Poster presented at: The American Academy of Physical Medicine and Rehabilitation 67th Annual Assembly and Technical Exhibition. Honolulu, HI; November 2006.
Khan AS, Harden RN, Gagnon C, Zinke J, Gallizzi M, Kuiken T. An evaluation of post-amputation limbs using infrared telethermography, temperature strips and physical examination. Poster presented at: The 67th Annual Assembly of the American Academy of Physical Medicine and Rehabilitation. Honolulu, HI; November 2006.
Poster presented at: The American Academy of Physical Medicine and Rehabilitation 67th Annual Assembly and Technical Exhibition. Honolulu, HI; November 2006.
2007
Gallizzi M, Gagnon C, Harden RN, Stanos S, Khan A. Medication Quantification Scale Version III: Internal validation of detriment weight using a chronic pain population. Poster presented at:: The Midwest Pain Society. Chicago, IL; October 2007.
An examination of prognostic indicators for failed back surgery using psychometrics and pain medication usage. Poster presented at: The Midwest Pain Society. Chicago, IL; October 2007.
Sarin RR, Van der Ende GJ, Graciosa JR, Gagnon CM, Harden RN. A comparison of sympathetic skin response and skin conductance response testing to evaluate autonomic function in thoracic spinal cord injury associated with chronic pain. Poster presented at: The Midwest Pain Society. Chicago, IL; October 2007.
Injured worker job accommodations, sources of work support, and job satisfaction: Since when was support a bad thing? Poster presented at: The Midwest Pain Society. Chicago, IL; October 2007.
Vadada K, Harden RN, Gagnon CM, Gallizzi MA, Arnold N. An investigation of sympathetic reactivity to a cold pressure challenge: A comparison of residual limbs to unaffected contralateral limbs. Poster presented at: The Midwest Pain Society. Chicago, IL; October 2007.
Weber NH, Harden RN, Gagnon CM. Is post amputee pain a sympathetically maintained pain? Poster presented at: The Midwest Pain Society. Chicago, IL; October 2007.
Weber NH, Vadada K, McDonald AM, Graciosa J, Harden RN, Gagnon CM. Development of a pain assessment scale for patients with moderate to severe brain injury: A pilot study. Poster presented at: The Midwest Pain Society. Chicago, IL; October 2007.
2008
Carroll R, Mac Donald AM, Weber NH, Gagnon CM, Leinberger KM, Harden RN. Development of a Pain Assessment Scale for Patients with Moderate to Severe Brain Injury: A Pilot Study. Journal of Pain. 2008; 9(4) 65.
Gagnon C, Stanos S, Van der Ende G, Rader L, Harden RN. Efficacy of an Interdisciplinary Pain Management Program with Workers Compensation Patients. Journal of Pain. 2008; 9(4): 68.
Scheuer ML, Gagnon CM, Van der Ende GJ, Gallizzi M, Rader L, Stanos S, Harden RN. Relationships of Job Accommodations, Stressors, and Sources of Support for Employed Chronic Pain Patients with Job Satisfaction. Journal of Pain 2008; 9(4) 75.
Wallach GI, Gagnon CM, Harden RN. A Comparison of Two Wind-Up Methodologies in Patients with Osteoarthritis vs. Normal Controls. Journal of Pain 2008; 9(4) 10.
2009
Harden RN, Gagnon CM, Wallach G. Central Sensitization in Osteoarthritis of the Knee. Journal of Pain. 2009; 10(4) S13.
Gallizzi MA, Gagnon C, Gracoisa J, Bruel S, Harden RN. International comparison of prescribing practices for Complex Regional Pain Syndrome (CRPS): A practical application of the Medication Quantification Scale III.Presented at: The 70th Annual Assembly of the American Academy of Physical Medicine and Rehabilitation. Austin, TX; October 2009.
2011
Saracoglu M, Graciosa JR, Kuroda MM, Harden RN. Perceived Pain, Disability and Psychometric Measures in Neuropathic versus Nociceptive Pain. Poster presented at the American Academy of Pain Medicine Annual Meeting, March 2011.
Swank S, Harden RN, Stegena N. Somatic Dysfunction in Amputees: A Pilot Study. Poster presented at the American Academy of Pain Medicine Annual Meeting, March 2011.
Saracoglu M, Wallach G, Graciosa JR, Kuroda MM, Harden RN. The Impact Of Demographic Variables On Two Common Pain And Quality Of Life Assessment Tools In The Knee Osteoarthritis Model. Poster presented at the American Academy of Pain Medicine Annual Meeting, March 2011.
Mehta N, Graciosa JR, Harden RN. Vasomotor Dysfunction In SCI Patients Measured Via Infrared Telethermography. Poster presented at the American Academy of Pain Medicine Annual Meeting, March 2011.
Swank S, Harden RN, Tong R. Anxiety and Disability Correlates in Post-Amputee Pain. Poster presented at the American Pain Society Annual Meeting, May 2011.
