Todd Kuiken, MD, PhD - Rehabilitation Institute of Chicago

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  • 182-bed inpatient hospital in the heart of Chicago
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  • Only rehabilitation hospital with eight federally designated research centers
  • 370+ active research projects in neuroscience, bionics, robotics, and musculoskeletal medicine
  • Academic home of Physical Medicine & Rehabilitation Department, Northwestern University Feinberg School of Medicine

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Todd Kuiken View my video

Todd Kuiken, MD, PhD

  • Director, Center for Bionic Medicine, RIC
  • Director, Amputee Services, RIC
  • Associate Dean, Academic Affairs, Feinberg School of Medicine, Northwestern University
  • Professor, PM&R, Feinberg School of Medicine, Northwestern University
  • Professor, Dept. of Surgery, Feinberg School of Medicine, Northwestern University

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  • Conditions Amputation Team
Year began practicing:
Year joined staff:
Year began practicing in specialty:

Conditions Treated / Services

  • Amputation and Limb Deficiencies
  • Amputation/Amputee
  • Congenital Limb Deficiency
  • Gait Disorders
  • Limb Deficiency

Clinical Interests

Amputation and Limb Deficiency/Deficiencies, Gait Disorders

Education, Residency and Internship


Duke University, BS, Biomedical Engineering
Northwestern University, PhD, Biomedical Engineering
Northwestern University Feinberg School of Medicine, MD


Evanston Hospital


RIC/Northwestern Feinberg School of Medicine, PM&R


RIC, Research Fellowship

Additional Information

Patient Story


Teaching or Professional Positions

  • Professor, Departments of PM&R, Biomedical Engineering Department, and Surgery, Northwestern University

Professional Memberships

  • National Institutes of Health
    • Advisory Board of the NCMMR, (2011 - present)
    • Research Grant Review Panels, invited member
  • American Academy of Physical Medicine and Rehabilitation, Member, (1995 - present)
    • Representative for Centers for Medicare, Medicaid Serves Negotiated Rulemaking Committee on Orthotics and Prosthetics, (2002 - 2003)
    • Past Chairman of Prosthetics, Orthotics, Wheelchairs and Human Biomechanics SIG
  • Associate Editor, Archives of PM&R (2003 - 2004)
  • Association of Academic Physiatrists, Member, (1995 - 2004)
  • International Society of Prosthetics and Orthotics, Member, ( 2003 - present)
  • American Academy of Orthotists and Prosthetists, Member
    • Invited participant in the Clinical Standards of Practice Consensus Conference on Standards of Care for the Lower Limb Amputee
  • Society for Neuroscience, (2005 - present)
  • Institute of Electrical and Electronics Engineers, Senior Member, (1999 - present)
  • IEEE Transactions in Neural Systems and Rehabilitation Engineering, Scientific Advisory Board, (2005 - present) 
  • Health Volunteers Overseas Lectureship.  Gave one week course on ‘Care of the Amputee, Prosthetics and Orthotics’ to Vietnamese physicians in Hanoi, Vietnam, (June 1999) 

Honors & Awards

  • Top news from the world of science in 2011, Science News for Rubber Hand Illusion paper, Brain. Brain 2011: 1-12.
  • Top 1% of Physicians, US News and World Report, 2011-12.
  • Top 40 visionaries in Chicago. Chicago, Magazine, December. 2010           
  • Best Scientific Paper at Int’l Soc. of Prosthet. and Orthot., Leipzig, Germany, 2010.
  • Honorary Doctorate from University of Central Iowa, October, 2009
  • Engineer of the Year Finalist.  Design News, August 2008.
  • Inducted in to the University of Idaho Hall of Fame, May 2008.
  • Creative Clinician Award, American Academy of Orthotist and Prosthetists, February 2008.
  • Scientific American 50, Award for top 50 technology leaders, Scientific American Magazine. December 2007.
  • Forchheimer Prize Paper in Prosthetics and Orthotics International, International Society of Prosthetics and Orthotics, August 2007
  • Health Breakthrough Award, Ladies Home Journal, August 2007
  • Chicagoan of the Year, Chicago Magazine, January 2007
  • Engineering Achievement Award, Illinois Engineering Council, October, 2006
  • Named ‘A Modern Leonardo da Vinci’ by the Chicago Museum of Science and Industry, June 2006
  • Bionic Arm-Best Innovations 2006, America’s 100 Best, Readers Digest Magazine, May 2006.
  • Grand Award Winner, Best New Healthcare Technology of 2005, Popular Science Magazine, December, 2005
  • The da Vinci Award® ‘honoring outstanding engineering achievements relative to design process, product design and applied research as relate to accessibility and universal design issues’, National Multiple Sclerosis Society, October, 2005
  • Best Doctors in US, Castle-Connelly, Every year since 2003.
  • Best Doctors in Chicago, Chicago Magazine, each year since 2004
  • Best Doctor in Chicago, Chicago Hospital News, September, 2004
  • Breakthrough Doctors, Chicago Magazine, January, 2003 and 2007
  • Best Paper, Runner-Up.  IX World Congress of the International Society for Prosthetics and Orthotics, Amsterdam, Netherlands, June, 1998
  • The Scholl Recognition Award for Rehabilitation Research, 1995
  • Sara Baskin Research Award, 1992


Birdwell J, Hargrove L, Kuiken TA, and Weir R. Isolated Activation of the Extrinsic Thumb Muscles and Compartments of the Extrinsic Finger Muscles. Submitted to J Neurophys August, 2012.

Chen A, Yao J, Kuiken TA and Dewald JPA. Cortical activity and reorganization following upper-limb amputation and subsequent targeted reinnervation. Submitted to Exp Brain Res, May 2012.

P, Ko JH, O'Shaughnessy KD, Kuiken TA, Pohlmeyerm EA and Dumanian, GA. The effects of targeted muscle reinnervation on neuromas in a novel rabbit rectus abdominis flap model. J Hand Surg 37A:1609–1616, August 2012.

Bunderson NE, Kuiken TA. Quantification of Feature Space Changes with Experience during Electromyogram Pattern Recognition Control. IEEE Trans Rehab and Neural Sys. 99(1), January 2012. DOI.1109/TNSRE.2011.2182525  

Young AJ, Hargrove LG, and Kuiken TA.  Improving Myoelectric Pattern Recognition Robustness to Electrode Shift by Changing Interelectrode distance and Electrode Configuration. IEEE Trans BME 59(3): 645-53. March 2012.  DOI 10.1109/TBME.2011.2177662.

Yerneni S, Dhaher Y, Kuiken TA. A computational model for stress reduction at the skin-implant interface of osseo-integrated prostheses. J Biomed Materials Res, 100A:911–917. January 2012, DOI: 10.1002/jbm.a.34028.

Agnew SP, Schultz AE, Dumanian GA, and Kuiken TA. Targeted Reinnervation in the Transfemoral Amputee: A Preliminary Study of Surgical Technique. Plastic and Reconstructive Surgery 129(1):187-194, January 2012.

Ko JH, Kim PS, O'Shaughnessy XD, Ding X, Kuiken TA and Dumanian GA. Quantitative Evaluation of Gross Versus Histologic Neuroma Formation in a Rabbit Forelimb Amputation Model: Potential Implications for the Operative Treatment and Study of Neuromas. J Brachial Plexus and Peripheral Nerve Injury. 6:8, October, 2011.

Kryger M, Schultz AE, and Kuiken TA. Pattern recognition control of multifunctional myoelectric prostheses by patients with congenital transradial limb defects. P&O Intl, 35(4): 401-407, December 2011.

Young AJ, Hargrove LJ, and Kuiken TA. The effects of electrode size and orientation on the sensitivity of myoelectric pattern recognition systems to electrode shift. IEEE Trans Biomed Eng, 58(9):2537-2544, Sept 2011.

Simon AM, Hargrove LJ, Lock BA and Kuiken TA. The Target Achievement Control Test: Evaluating real-time myoelectric pattern recognition control of multifunctional upper-limb prosthesis. J Rehab Res and Dev, 48(6): 619-628, July 2011.

Lipschutz RD, Lock BA, Sensinger J and Kuiken TA. Use of a Two–Degree of Freedom Joystick for Control of Externally Powered, Shoulder Disarticulation Prostheses.  J Rehab Res and Dev, 48(6): 661-668, July 2011.

Corbett E, Perrault E and Kuiken TA. An Evaluation of Control Interfaces for Upper Limb Prostheses. J Rehab Res and Dev, 48(6): 629-642, July 2011.

Simon AM, Hargrove LJ, Lock BA and Kuiken TA. A decision-based velocity ramp for minimizing the effect of misclassifications during real-time pattern recognition control. IEEE Trans BME, 48(6):619-628, May 2011.

Rouse E, Nahlik D, Peshkin M and Kuiken TA. Development of a magnet tracking algorithm for an Osseo-Magnetic Link. IEEE Trans Rehab and Neural Sys, 19(2): 213-220, 2010.

Shultz AE and Kuiken TA. Neural Interfaces for Control of Upper Limb Prostheses: The State-of-the-Art and Hopes for the Future. PM&R,3(1):55-67, 2011.

Hargrove L, Simon AM, Lipschutz R and Kuiken TA. Real-Time Myoelectric Control of Knee and Ankle Motions for Transfemoral Amputees. JAMA,  305(15):1542-1544, 2011

Smith LH, Hargrove LJ, Lock BA and Kuiken TA, Determining the optimal window length for pattern recognition-based myoelectric control: balancing the competing effects of classification error and controller delay. IEEE Trans Rehab and Neural Sys, 19(2): 186-192, 2011.

Marasco PD, Kim K, Colgate JE, Peshkin MA and Kuiken TA. Robotic touch shifts perception of embodiment to a prosthesis in targeted reinnervation amputees. Brain 2011: 1-12, doi: 10.1093/brain/awq361.

Marasco PD and Kuiken TA. Median nerve redirection following forelimb amputation reactivates the forepaw barrel subfield in adult rats; with correlations to Targeted Reinnervation in a human amputeeJ Neuroscience, 30(47):16008-16014, November 2010.

Tkach D, Huang H and Kuiken TA. Study of Stability of Time-Domain Features for Electromyographic Pattern Recognition. J Neuro Eng and Rehab, 7:21, 2010.

Li G, Schultz A and Kuiken TA. Quantifying Pattern Recognition Based Myoelectric Control of Multifunctional Transradial Prostheses. IEEE Trans Rehab and Neural Sys, 18(2):185-192, 2010.

Kim PS, Ko J, O'Shaughnessy KK, Kuiken TA and Dumanian G. Novel Model for End-Neuroma Formation in the Amputated Rabbit Forelimb. J Brachial Plexus and Peripheral Nerve Injury, 5(6)1-8, 2010.

Su PF, Gard SA, Lipschutz R and Kuiken TA. The Effects of Increased Prosthetic Ankle Motions on the Gait of Persons with Bilateral Transtibial Amputations. Am J PM&R, 89(1):34-47, 2010.

Katholia B, Solty N, Schmidt J, Heelan J, Kuiken TA and Gaebler-Spira DJ. The fitting of a unilateral shoulder disarticulation prosthesis after electrical burn injury: A case report. J Ped Rehab Med, 2(1):229–233, 2009. 

Sensinger JW, Schultz AE, and Kuiken TA. Examination of force discrimination in human upper limb amputees with reinnervated limb sensation following peripheral nerve transfer. IEEE Trans Rehab and Neural Sys, 17 (5): 438-444. 2009.

Hargrove L, Zhou P, Englehart K and Kuiken TA. The Effect of ECG Interference on Pattern Recognition Based Myoelectric Control for Targeted Muscle Reinnervated Patients. IEEE Trans BME. 56(9): 2197-2201, 2009.

Stubblefield K and Kuiken TA. Occupational Therapy Protocol for Amputees with Targeted Muscle Reinnervation. J Rehab Res and Dev. 46(4): 481–488, 2009.

Dumanian, GA, Ko, J., O'Shaughnessy, KD, Kim, PS, Wilson, CJ and Kuiken, TA. Targeted Reinnervation for Transhumeral Amputees: Current Surgical Technique and Update on Results. Plast and Reconstr Surg 124(3): 863-869, 2009.

Huang H, Zhou P, Li G and Kuiken TA. Using Spatial Filters to Improve Targeted Muscle Reinnervation Based Neural Control Interface. Annals of BME, 37(9):1849-59, 2009.

Sensinger JW, Lock B and Kuiken TA. Adaptive Pattern Recognition of Myoelectric Signals: Exploration of Conceptual Framework and Practical Algorithms. IEEE Trans Rehab and Neural Sys, 17(3): 270-278, 2009.

Marasco PD, Schultz AE and Kuiken TA. Tactile spatial acuity of reinnervated skin following the surgical redirection of hand nerves to the chest. Brain, 132(6): 1441-1448, 2009.

Kuiken TA, Li G, Lock BA, Lipschutz RD, Miller LA, Stubblefield KA, and Englehart K. Targeted Muscle Reinnervation for Real-Time Myoelectric Control of Multifunctional Artificial Arms. JAMA 301(6):619-628, 2009.

Schultz A, Marasco P and Kuiken TA. Vibrotactile stimulation of amputees’ reinnervated chest skin following nerve transfer surgery is perceived on the missing limb but is perceived at near-normal thresholds. Brain Research, 1251:121-129, 2009.

Huang H, Kuiken TA and Lipschutz R. Strategy for Identifying Locomotion Modes using Surface Electromyography. IEEE Trans BME, 56(1), 2009.

Miller LA, Lipschutz RD, Stubblefield KA, Lock BA, Huang H, Williams TW, Weir RF, and Kuiken TA. Control of a Six Degree-of-freedom Prosthetic Arm after Targeted Muscle Reinnervation Surgery. Arch of PM&R, 89: 2057-65, 2008.

Li G and Kuiken TA. Modeling of Prosthetic Limb Rotation Control by Sensing Rotation of Residual Arm Bone. IEEE Trans BME, 55(9)2134-2142, 2008.

Su PF, Gard SA, Lipschutz R and Kuiken T. Differences in Gait Characteristics between Persons with Bilateral Transtibial Amputations Due to Peripheral Vascular Disease and Trauma, with Able-bodied Ambulators. Arch of PM&R, 89(7):1386-94, 2008.

O’Shaughnessy KD, Dumanian GA, Lipschutz RD, Miller LA, Stubblefield K and Kuiken TA. Targeted reinnervation to improve prosthesis control in transhumeral amputees. A report of three cases. J Bone and Joint Surg Am, 90:393-400, 2008.

Miller LA, Stubblefield KA, Lipschutz RD, Lock BA and Kuiken TA. Improved Myoelectric Prosthesis Control Using Targeted Reinnervation Surgery: A Case Series. IEEE Trans Rehab and Neural Sys, 16(1):46-50, 2008.

Huang H, Zhou P, Li G and Kuiken TA. An analysis of EMG electrode configuration for targeted muscle reinnervation based neural machine interface. IEEE Trans Rehab and Neural Sys, 16(1):37-45, 2008.

Tu FF, Fitzgerald CM, Kuiken TA, Farrell T and Harden RN. Vaginal Pressure-Pain Thresholds: Initial Validation and Reliability Assessment in Healthy Women. Clini J of Pain, 24(1):45-50, 2008.

Kuiken TA, Marasco PD, Lock BA, Harden RN and Dewald JP. Redirection of cutaneous sensation from the hand to the chest skin of human amputees with targeted reinnervation. Proc Natl Acad Sci USA, 104(50):20061-6, 2007.

Su PF, Gard SA, Lipschutz RD and Kuiken TA. Gait characteristics of persons with bilateral transtibial amputations. J Rehab Res and Dev, 44(4): 491-502, 2007.

Zhou P, Lowery ML, Englehart KB, Huang H, Li G, Hargrove L, Dewald JP and Kuiken TA. Decoding a new neural machine interface for control of artificial limbs. J Neurophysiol 98(5): 2974-2982, 2007.

Schultz A, Baade SP and Kuiken TA. Expert Opinion on Factors of Success for Upper-Limb Prostheses.  J Rehab Res and Dev, 4(4): 483-90, 2007.

Kuiken TA and Soltys N. An Economical Cosmetic Covering for Preparatory Prostheses. J Prosth and Orth, 19(2):37-39, 2007.

Kuiken TA, Miller LA, Lipschutz RD, Lock B, Stubblefield K, Marasco P, Zhou P and Dumanian G. Targeted Reinnervation for Enhanced Prosthetic Arm Function in Woman with a Proximal Amputation: a case study. Lancet, 369(9558): 371-80, 2007.

Tu FF, Fitzgerald CM, Kuiken TA, Farrell T and Harden RN. Comparative Measurement of Pelvic Floor Pain Sensitivity in Chronic Pelvic Pain. Ob & Gyn , 110:1244-1248, 2007.

Zhou P, Lock B and Kuiken TA. Real Time ECG Artifact Removal for Myoelectric Prosthesis Control. Physiol Meas, 28(4): 397-413, 2006.

Zhou P and Kuiken TA. Eliminating cardiac contamination from myoelectric control signals developed by targeted muscle reinnervation. Physiol Meas. 27(12):1311-27, 2006.

Lowery MM, Weir RF and Kuiken TA. Simulation of intramuscular EMG signals detected using implantable myoelectric sensors (IMES). IEEE Trans BME 53(10): 1926-33, 2006.

Hijjawi JB, Kuiken TA, Lipschutz, RD, Miller LA, Stubblefield KA and Dumanian GA.  Improved myoelectric prosthesis control accomplished using multiple nerve transfers. Plast and Reconstr Surg, 118(7):1573-78, 2006.

Lipschutz RD, Kuiken TA, Dumanian GA, Miller, LA Dumanian GA, and Stubblefield KA. Shoulder disarticulation externally powered prosthetic fitting following targeted muscle reinnervation for improved myoelectric prosthesis control. J Prosth and Orth, 18(2):28-34, 2006

Kuiken TA, Schechtman, L and Harden RN. Phantom Limb Pain Treatment with Mirtazapine: A Case Series. Pain Practice, 5(4):356-358, December 2005.

Harden RN, Houle TT, Green S, Remble TA, Weinland SR, Colio S, Lauzon J and Kuiken, T.  Biofeedback in the treatment of phantom limb pain: a time-series analysis. Appl Psychophysiol Biofeedback. 30(1):83-93, 2005.

Stoykov NS, Lowery MM, and Kuiken TA.  A finite-element analysis of the effect of muscle insulation and shielding on the surface EMG signal. IEEE Trans BME 52(1):117-21, 2005.

Kuiken TA, Dumanian GA, Lipschutz RD, Miller LA and Stubblefield KA. The use of targeted muscle reinnervation for improved myoelectric prosthesis control in a bilateral shoulder disarticulation amputee.  Prosth and Orth Intl, 28(3):245-253, 2004.

Lowery MM, Stoykov NS, Dewald JP and Kuiken TA.  Volume conduction in an anatomically based surface EMG Model.  IEEE Trans BME, 51(12): 2138-2147, 2004.

Kuiken TA, Amir H and Scheidt RA.  Computerized biofeedback knee goniometer: acceptance and effect on exercise behavior in post TKA rehabilitation, Arch of PM&R, 85(6):1026-30, 2004.

Kuiken TA. Consideration of nerve-muscle grafts to improve the control of artificial arms.  Jof Tech and Disability, 15(2):105-111, 2003.

Stoykov NS, Kuiken TA, Lowery MM and Taflove A.  Finite-element time-domain algorithms for modelling linear Debye and Lorentz dielectric dispersions at low frequencies.  IEEE Transactions on Biomedical Engineering 50(9): 1100-1107, 2003.

Lowery MM, Stoykov NS and Kuiken TA.  Independence of myoelectric control signals examined using a surface EMG model.  IEEE Transactions on Biomedical Engineering, 50(6): 789-793, 2003.

Kuiken TA, Lowery MM and Stoykov NS. The effect of subcutaneous fat on myoelectric signal amplitude and cross-talk.  Prosth and Orth Intl 27(1): 48-54, 2003.

Lowery MM, Stoykov NS, Taflove A and Kuiken TA. A simulation study of surface EMG cross-talk as an estimate of surface EMG cross-talk. Journal of Applied Physiology 94(4): 1324-1334, 2003.

Hu A, Harden N and Kuiken TA. Topiramate for relief of phantom limb pain in a traumatic amputee. J Back and Musculoskeletal Rehab 16: 141-143, 2002.

Stoykov NS, Lowery MM, Taflove A and Kuiken TA.  Frequency and time domain FEM models of EMG: capacitive effects and aspects of dispersion. IEEE Transactions in Biomedical Engineering 49(8): 763-72, 2002.

Lowery MM, Stoykov NS, Taflove A and Kuiken TA.  A multi-layer finite element model of the surface EMG signal. IEEE Transactions in Biomedical Engineering 49(5):446-54, 2002.

Kuiken TA, Stoykov NS, Popovic M, Lowery MM and Taflove A.  Finite element modeling of electromagnetic signal propagation in a phantom arm.  IEEE Transactions in Neural Systems and Rehabilitation Engineering, 9(4): 346-354, December, 2001.

Kuiken TA and Smith J.  Success treatment of dysesthetic pain with a combination of tricyclic antidepressant and carbamazepine, Jo of Back and Musculoskeletal Rehab, 14(12):17-20, 2000. 

Arfken CL, Lichtenberg PA and Kuiken TA. Importance of comorbid illnesses in predicting mortality for geriatric rehabilitation.  Topics in Geriatric Rehab, 13: 69-76, 1998.

Kuiken TA and Prather HB.  A computer education program to improve physician awareness of rehabilitation hospital charges. Arch PM&R, 79(8): 910-914, 1998.

Kuiken TA, Prather HB, and Bloom S. Physician awareness of rehabilitation costs. Am J of PM&R, 75(6): 416-421, 1996. 

Kuiken TA, Rymer WZ and Childress DS. The hyper-reinnervation of rat skeletal muscle. Brain Research 676(1): 113-123, 1995. 

Kuiken TA.  An ambulation aid for foot and ankle injuries.  PT Journal, 66:1413-1414, 1986.

Research Interests

Care of people with amputations Development of neural interfaces for Amputees Control of artificial limbs Design of artificial limbs

Certifications & Licenses

  • PM&R, #5099 1996 Medical Licencse is Illinois

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