Li-Qun Zhang, PhD - Rehabilitation Institute of Chicago

Skip to Content


  • Only Hospital Ranked #1 in America by U.S. News & World Report since 1991
  • 800,000+ outpatient visits each year
  • 5,000+ inpatients treated each year, system-wide
  • 50+ sites of care throughout Illinois and Indiana
  • One of only 2% of hospitals to receive three consecutive Magnet Recognitions for Nursing Excellence.
  • 182-bed inpatient hospital in the heart of Chicago
  • Largest rehabilitation research center in the world
  • Only rehabilitation hospital with eight federally designated research centers
  • 370+ active research projects in neuroscience, bionics, robotics, and musculoskeletal medicine
  • Academic home of Physical Medicine & Rehabilitation Department, Northwestern University Feinberg School of Medicine

Clinical Trials

Did you know you can help advance the science of rehabilitation medicine while benefiting from the latest research findings?

You can – by joining a clinical trial! See a list of our Research Studies & Clinical Trials.

Your RIC Doctor Search Result

Li-Qun Zhang

Li-Qun Zhang, PhD

  • Senior Research Scientist, SMPP, RIC
  • Professor, PM&R , Feinberg School of Medicine, NU
  • Professor, Orthop Surg, Feinberg School of Medicine, NU
  • Professor, BME, McCormick School of Engineering, NU


Education, Residency and Internship


Tsinghua University, Beijing, China, BS, Electrical Eng.
Vanderbilt University, TN, MS, Biomed. Eng.
Vanderbilt University, TN, PhD, Biomed. Eng.


Rehabilitation Institute of Chicago, Post Doctoral Fellow



Chen, K., Wu, Y.-N., Ren, Y., Liu, L., Gaebler-Spira, D., Tankard, K., Lee, J., Song, W., Wang, M., and Zhang, L.-Q., 2016. Home versus laboratory-based robotic ankle training for children with cerebral palsy: A pilot randomized controlled trial assessing feasibility and outcomes. Arch Phys Med Rehab. in press.

Wu, Y.-N., Ren, Y., Tsai, L.-C., Gao, F., and Zhang, L.-Q., 2016. In Vivo Simultaneous Evaluations of Sarcomere Imaging and Muscle Fiber Tension. J Biomech. in press.

Lee, S. S. M., Gaebler-Spira, D., Zhang, L.-Q., Rymer, W. Z., and Steele, K. M., 2016. Use of shear wave ultrasound elastography to quantify muscle properties in cerebral palsy. Clin Biomech. 31, 20-28.

Lin, C., Tsai, L.-C., Press, J. M., Ren, Y., Chung, S. G., and Zhang, L.-Q., 2016. Lower Limb Muscle Activation Patterns During Off-Axis Elliptical Compared to Conventional Gluteal Muscle Strengthening Exercises. J of Sport Rehab. in press.

Guelich, D. R., Xu, D., Koh, J. L., Nuber, G. W., and Zhang, L.-Q., 2016. Different Roles of the Medial and Lateral Hamstrings in Unloading the Anterior Cruciate Ligament. The Knee. 23, 97-101.


Zhao, H., Ren, Y., Roth, E. J., Harvey, R., and Zhang, L.-Q., 2015. Concurrent Biomechanical Changes of Soleus and Gastrocnemius Muscle Fascicles and Achilles Tendon Post Stroke. J Appl Physiol. 118, 863–871.

Tsai, L.-C., Lee, S. J., Yang, A., Ren, Y., Press, J. M., and Zhang, L.-Q., 2015a. Effects of off-axis elliptical training on reducing pain and improving knee function in individuals with patellofemoral pain. Clin J Sports Med. 25, 487-493.

Lee, S. J., Ren, Y., Kang, S. H., Geiger, F., and Zhang, L.-Q., 2015. Pivoting neuromuscular control and proprioception in females and males. Euro J Appl Physiol. 115, 775-784.

Xu, D., Guo, X., Yang, C.-Y., and Zhang, L.-Q., Assessment of Hyperactive Reflexes in Patients with Spinal Cord Injury. BioMed Research Intl. 2015.

Lee, S. J., Ren, Y., Chang, A. H., Geiger, F., and Zhang, L.-Q., 2014. Effects of Pivoting Neuromuscular Training on Pivoting Control and Proprioception. Med Sci Sports Ex. 46, 1400-1409.

Sukal-Moulton, T., Clancy, T., Zhang, L.-Q., and Gaebler-Spira, D., 2014. Clinical application of a robotic ankle training program for cerebral palsy compared to the research laboratory application: Does it translate to practice? Arch Phys Med Rehab. 95, 1433-1440.

Kang, S. H., Lee, S. J., and Zhang, L.-Q., 2014. Real-Time Tracking of Knee Adduction Moment in Patients with Knee Osteoarthritis. J of Neurosci Meth. 231, 9-17.

Kang, S. H., Lee, S. J., Ren, Y., and Zhang, L.-Q., 2014. Real-Time Knee Adduction Moment Feedback Training Using an Elliptical Trainer. IEEE Trans Neural Syst Rehab Eng. 22, 334 - 343.

Zhang, L.-Q., Chen, K., Kang, S. H., Sliwa, J. A., Cohen, B. A., Rymer, W. Z., and Wang, L., 2014. Characterizations of reflex and nonreflex changes in spastic multiple sclerosis. J Neurosci Meth. 231, 3-8.

Fung, D. T., Lee, S. J., Ren, Y., Kang, S. H., Liu, S. Q., and Zhang, L.-Q., 2014. Impingement Analysis with 3-D Geometric Characterizations of ACL Pseudofibers and Intercondylar Notch. J Med Biol Eng. 34, 116-122.

Haddad, S. L., Hsu, A. R., Templin, C. R., Ren, Y., Stewart, B., Kohli, N. S., and Zhang, L.-Q., 2014. Effects of Continuous Irrigation During Burring on Thermal Necrosis and Fusion Strength in a Rabbit Arthrodesis Model. Foot & Ankle Int. 35, 796 -801.

Chang, A. H., Lee, S. J., Zhao, H., Ren, Y., and Zhang, L.-Q., 2014. Impaired Varus-Valgus Proprioception and Neuromuscular Stabilization in Medial Knee Osteoarthritis. J Biomech. 47, 360-366.


Ren, Y., Lee, S. J., Park, H. S., and Zhang, L. Q., 2013. A Pivoting Elliptical Training System for Improving Pivoting Neuromuscular Control and Rehabilitating Musculoskeletal Injuries. . IEEE Tran Neural Syst Rehab Eng, 21, 860-868. Zhang, L.-Q., Chung, S. G., Ren, Y., Liu, L., Roth, E. J., and Rymer, W. Z., 2013. Simultaneous characterizations of reflex and nonreflex dynamic and static changes in spastic hemiparesis. J Neurophysiol. 110, 418-430.

Waldman, G., Yang, C.-Y., Ren, Y., Liu, L., Guo, X., Harvey, R. L., Roth, E. J., and Zhang, L.-Q., 2013. Effects of robot-guided passive stretching and active movement training of ankle and mobility impairments in stroke. NeuroRehab. 32, 625-634.

Ren, Y., Kang, S. H., Park, H.-S., Wu, Y.-N., and Zhang, L.-Q., 2013. Developing a multi-joint upper limb exoskeleton robot for diagnosis, therapy, and outcome evaluation in neurorehabilitation. IEEE Tran Neural Syst Rehab Eng. 21:490-9.

Lee, S. J., Ren, Y., Geiger, F., and Zhang, L.-Q., 2013. Gender differences in offaxis neuromuscular control during stepping under a slippery condition. Euro J Appl Physiol. 113, 2857–2866.

Levin, S. D., Wellman, D., Liu, C., Li, Y., Ren, Y., Shah, N. A., and Zhang, L.-Q., 2013. Biomechanical strain characteristics of soft tissue biceps tenodesis and bony tenodesis. J Orthopaedic Sci. 18, 699-704.

Chilelli, B. J., Patel, R. M., Kalainov, D. M., Peng, J., and Zhang, L.-Q., 2013. Flexor Pollicis Longus Dysfunction After Volar Plate Fixation of Distal Radius Fractures. The J Hand Surg. 38, 1691-1697.

Yang, C.-Y., Guo, X., Ren, Y., Kang, S. H., and Zhang, L.-Q., 2013. Position-Dependent, Hyperexcitable Patellar Reflex Dynamics in Chronic Stroke. Arch Phy Med Rehab. 94, 391-400.

Schwartz, D. G., Kang, S. H., Lynch, T. S., Edwards, S., Nuber, G., Zhang, L.-Q., Saltzman, M., 2013. The anterior deltoid's importance in reverse shoulder arthroplasty: a cadaveric biomechanical study. J Shoulder Elbow Surg 22:357-64.

Liu, S. Q., Roberts, D., Zhang, B., Ren, Y., Zhang, L.-Q., and Wu, Y. H., 2013. Trefoil Factor 3 as an Endocrine Neuroprotective Factor from the Liver in Experimental Cerebral Ischemia/Reperfusion Injury. PLoS ONE. 8, e77732.

Kang, C., Yang, C.-Y., Kim, J. H., Moon, S.-K., Lee, S., Park, S.-A., Han, E.-H., and Zhang, L.-Q., 2013. The Effect of Continuous Epidural Electrical Stimulation on Neuronal Proliferation in Cerebral Ischemic Rats. Ann Rehabil Med. 37, 301-310.

Research Interests

development of intelligent rehabilitation devices to perform diagnosis, passive stretching and active movement treatments, and outcome evaluations of impaired limbs post stroke; investigate reflex/non-reflex factors contributing to impairments/spastic hypertonia at the joints, muscle fiber, and sarcomere levels; and mechanisms of knee injury & injury prevention; and load sharing among muscles and 3D mechanical actions of individual muscles

Office Information